HDAC6

GENE INFORMATION

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Gene name

HDAC6 (HGNC Symbol)

Synonyms

FLJ16239, HD6, JM21, KIAA0901

Description

histone deacetylase 6 (HGNC Symbol)

Entrez gene summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

p11.23

Chromosome location (bp)

48659784 - 48683392

Ensembl

ENSG00000094631 (version 73.37)

Entrez gene

10013

UniProt

Q9UBN7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBN7

Antibodypedia

HDAC6 antibodies
 

PROTEIN VIEW

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 « 
 
HDAC6-001
 
HDAC6-007
 
HDAC6-015
 
HDAC6-016
 
HDAC6-017
 
HDAC6-020
 
HDAC6-021
 
HDAC6-023
 
HDAC6-028
 
HDAC6-030
 
HDAC6-031
 
HDAC6-201
 
HDAC6-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HDAC6-001 ENSP00000334061
ENST00000334136
Q9UBN7
Show all »
Show » Show » 1215 131.4 No 0
HDAC6-007 ENSP00000365831
ENST00000376643
A6NDI8
Show all »
Show » 210 23.4 No 0
HDAC6-015 ENSP00000402189
ENST00000426196
E7EPS2
Show all »
Show » 269 30.3 No 0
HDAC6-016 ENSP00000397697
ENST00000430858
84 8.7 No 0
HDAC6-017 ENSP00000365804
ENST00000376619
Q9UBN7
Show all »
Show » Show » 1215 131.4 No 0
HDAC6-020 ENSP00000392815
ENST00000423941
C9J172
Show all »
Show » 142 15.9 No 0
HDAC6-021 ENSP00000403370
ENST00000438518
C9JEF4
Show all »
Show » 51 5.6 No 0
HDAC6-023 ENSP00000365795
ENST00000376610
A6NDI8
Show all »
Show » 210 23.4 No 0
HDAC6-028 ENSP00000393916
ENST00000441703
E9PEH1
Show all »
Show » 161 18.2 No 0
HDAC6-030 ENSP00000402751
ENST00000443563
E7EP63
Show all »
Show » 167 18.9 No 0
HDAC6-031 ENSP00000394377
ENST00000440653
E7ER52
Show all »
Show » 171 19.3 No 0
HDAC6-201 ENSP00000398801
ENST00000413163
E7EUZ1
Show all »
Show » Show » 296 33.3 No 1
HDAC6-202 ENSP00000398566
ENST00000444343
B4DZH6
Show all »
Show » Show » 1229 132.8 No 0