KCNK16

GENERAL INFORMATION

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Gene name

KCNK16

Gene description

Potassium channel, subfamily K, member 16

Protein class

Predicted membrane proteins
Transporters
Voltage-gated ion channels

Predicted localization

Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (duodenum, pancreas, stomach)
GTEx:Tissue enriched (pancreas)

Protein evidence

Evidence at transcript level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA016567
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (duodenum, pancreas, stomach)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (pancreas)

Organ

Expression



GENE INFORMATION

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Gene name

KCNK16 (HGNC Symbol)

Synonyms

K2p16.1, TALK-1, TALK1

Description

Potassium channel, subfamily K, member 16 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]

Chromosome

6

Cytoband

p21.2

Chromosome location (bp)

39314698 - 39322968

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000095981 (version 78.38)

Entrez gene

83795

UniProt

Q96T55 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96T55

Antibodypedia

KCNK16 antibodies


PROTEIN BROWSER

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ENST00000373227
 
ENST00000373229
 
ENST00000425054
 
ENST00000437525
 
ENST00000507712
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNK16-001 ENSP00000362326
ENST00000373229
Q96T55
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Show » Show » 309 34.2 No 6
KCNK16-002 ENSP00000415375
ENST00000437525
Q96T55
Show all »
Show » Show » 294 32.5 No 6
KCNK16-003 ENSP00000391498
ENST00000425054
Q96T55
Show all »
Show » Show » 322 35.8 No 5
KCNK16-004 ENSP00000362324
ENST00000373227
Q96T55
Show all »
Show » Show » 262 28.8 No 5
KCNK16-005 ENSP00000423842
ENST00000507712
D6RC57
Show all »
Show » Show » 197 21.4 No 4