SIRT1

SUBCELL ATLAS - HUMAN

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Summary

Mainly localized to the nucleus. In addition localized to the cytoplasm or mitochondria.

Main location

Nucleus

Additional location

Cytoplasm, Mitochondria

Reliability

Supportive

Protein evidence

High

Assay summary

Analysis based on two antibodies, HPA006295 and HPA052351, using immunoflourescence in human and mouse cells
 

 

 

 

 

 

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HPA006295
Cell line: U-2 OS
Location: Nucleus, Cytoplasm
Validation: Supportive
Cell line: A-431
Location: Nucleus, Cytoplasm
Validation: Supportive
Cell line: U-251 MG
Location: Nucleus, Cytoplasm
Validation: Supportive
HPA052351
Cell line: U-2 OS
Location: Nucleus but not nucleoli, Mitochondria
Validation: Supportive
Cell line: A-431
Location: Nucleus but not nucleoli
Validation: Supportive
Cell line: U-251 MG
Location: Nucleus but not nucleoli
Validation: Supportive