JAK2

GENE INFORMATION

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Gene name

JAK2 (HGNC Symbol)

Synonyms

JTK10

Description

Janus kinase 2 (HGNC Symbol)

Entrez gene summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

p24.1

Chromosome location (bp)

4985033 - 5128183

Ensembl

ENSG00000096968 (version 73.37)

Entrez gene

3717

UniProt

O60674 (UniProt - Evidence at protein level)

neXtProt

NX_O60674

Antibodypedia

JAK2 antibodies
 

PROTEIN VIEW

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JAK2-001
 
JAK2-201
 
JAK2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

JAK2-001 ENSP00000371067
ENST00000381652
O60674
Show all »
Show » Show » 1132 130.7 No 0
JAK2-201 ENSP00000440387
ENST00000539801
O60674
Show all »
Show » Show » 1132 130.7 No 0
JAK2-202 ENSP00000443103
ENST00000544510
F5H5U8
Show all »
Show » Show » 983 113.8 No 0