TRMT2A

GENERAL INFORMATION

? »

Gene name

TRMT2A

Gene description

TRNA methyltransferase 2 homolog A (S. cerevisiae)

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal cells showed nuclear staining which in several tissues was combined with additional cytoplasmic positivity.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA001077
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

TRMT2A (HGNC Symbol)

Synonyms

HTF9C

Description

TRNA methyltransferase 2 homolog A (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

20111866 - 20117392

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099899 (version 78.38)

Entrez gene

27037

UniProt

Q8IZ69 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IZ69

Antibodypedia

TRMT2A antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000252136
 
ENST00000403707
 
ENST00000404751
 
ENST00000439169
 
ENST00000444256
 
ENST00000444845
 
ENST00000445045
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRMT2A-001 ENSP00000252136
ENST00000252136
Q8IZ69
Show all »
Show » Show » 625 68.7 No 0
TRMT2A-002 ENSP00000384968
ENST00000404751
Q8IZ69
Show all »
Show » Show » 562 62 No 0
TRMT2A-003 ENSP00000395738
ENST00000439169
F2Z2W7
Show all »
Show » Show » 643 70.8 No 0
TRMT2A-005 ENSP00000385807
ENST00000403707
Q8IZ69
Show all »
Show » Show » 625 68.7 No 0
TRMT2A-006 ENSP00000393911
ENST00000445045
C9K041
Show all »
Show » Show » 120 12.9 No 0
TRMT2A-016 ENSP00000397744
ENST00000444845
H7C100
Show all »
Show » 158 17.2 No 0
TRMT2A-019 ENSP00000392261
ENST00000444256
Show » 142 15.1 No 0