CRKL

GENE INFORMATION

? »

Gene name

CRKL

Synonyms

Description

v-crk avian sarcoma virus CT10 oncogene homolog-like (HGNC Symbol)

Entrez gene summary

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]

Chromosome

22 (Chromosome progress)

Cytoband

q11.21

Chromosome location (bp)

21271714 - 21308037

Ensembl

ENSG00000099942 (version 73.37)

Entrez gene

1399

UniProt

P46109 (UniProt - Evidence at protein level)

neXtProt

NX_P46109

Antibodypedia

CRKL antibodies
 

PROTEIN VIEW

? »
 
 
 
CRKL-001
 
CRKL-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRKL-001 ENSP00000346300
ENST00000354336
P46109
Show all »
Show » Show » 303 33.8 No 0
CRKL-002 ENSP00000396646
ENST00000411769
P46109
Show all »
Show » Show » 303 33.8 No 0