DERL3

GENE INFORMATION

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Gene name

DERL3 (HGNC Symbol)

Synonyms

C22orf14, derlin-3, FLJ43842, IZP6, MGC71803

Description

derlin 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q11.23

Chromosome location (bp)

24176690 - 24181315

Ensembl

ENSG00000099958 (version 73.37)

Entrez gene

91319

UniProt

Q96Q80 (UniProt - Evidence at protein level)

neXtProt

NX_Q96Q80

Antibodypedia

DERL3 antibodies
 

PROTEIN VIEW

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DERL3-001
 
DERL3-002
 
DERL3-003
 
DERL3-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DERL3-001 ENSP00000384744
ENST00000406855
Q96Q80
Show all »
Show » Show » 239 26.6 No 4
DERL3-002 ENSP00000315303
ENST00000318109
Q96Q80
Show all »
Show » Show » 235 26.7 No 5
DERL3-003 ENSP00000419399
ENST00000476077
Q96Q80
Show all »
Show » Show » 205 23.4 No 5
DERL3-005 ENSP00000384473
ENST00000404056
E7EVA4
Show all »
Show » 178 19.1 No 0