CABIN1

GENE INFORMATION

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Gene name

CABIN1 (HGNC Symbol)

Synonyms

KIAA0330, PPP3IN

Description

calcineurin binding protein 1 (HGNC Symbol)

Entrez gene summary

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]

Chromosome

22 (Chromosome progress)

Cytoband

q11.23

Chromosome location (bp)

24407642 - 24574596

Ensembl

ENSG00000099991 (version 73.37)

Entrez gene

23523

UniProt

Q9Y6J0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6J0

Antibodypedia

CABIN1 antibodies
 

PROTEIN VIEW

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CABIN1-001
 
CABIN1-002
 
CABIN1-003
 
CABIN1-004
 
CABIN1-013
 
CABIN1-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CABIN1-001 ENSP00000381364
ENST00000398319
Q9Y6J0
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Show » 2220 246.4 No 0
CABIN1-002 ENSP00000384694
ENST00000405822
G5E9F3
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Show » 2141 237.6 No 0
CABIN1-003 ENSP00000412389
ENST00000445422
C9J068
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Show » 361 40.5 No 0
CABIN1-004 ENSP00000336991
ENST00000337989
B5MEB3
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Show » 590 63.3 No 0
CABIN1-013 ENSP00000394209
ENST00000454754
C9JT60
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Show » 357 40 No 0
CABIN1-014 ENSP00000263119
ENST00000263119
Q9Y6J0
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Show » 2220 246.4 No 0