TRIOBP

GENE INFORMATION

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Gene name

TRIOBP (HGNC Symbol)

Synonyms

DFNB28, HRIHFB2122, KIAA1662, Tara

Description

TRIO and F-actin binding protein (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

38093011 - 38172563

Ensembl

ENSG00000100106 (version 73.37)

Entrez gene

11078

UniProt

Q9H2D6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H2D6

Antibodypedia

TRIOBP antibodies
 

PROTEIN VIEW

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TRIOBP-001
 
TRIOBP-002
 
TRIOBP-005
 
TRIOBP-006
 
TRIOBP-008
 
TRIOBP-009
 
TRIOBP-010
 
TRIOBP-011
 
TRIOBP-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRIOBP-001 ENSP00000384312
ENST00000406386
Q9H2D6
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Show » 2365 261.4 No 0
TRIOBP-002 ENSP00000340312
ENST00000344404
H7BXW4
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104 11.3 No 0
TRIOBP-005 ENSP00000383913
ENST00000407319
F2Z2W0
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Show » 431 47.6 No 0
TRIOBP-006 ENSP00000386026
ENST00000403663
F8W6V6
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Show » 652 74 No 0
TRIOBP-008 ENSP00000396946
ENST00000418339
F6TR96
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Show » 265 29.6 No 0
TRIOBP-009 ENSP00000400680
ENST00000413051
H0Y5T8
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102 10.9 No 0
TRIOBP-010 ENSP00000387881
ENST00000417857
F6WYE2
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Show » 256 29 No 0
TRIOBP-011 ENSP00000407542
ENST00000452519
F6WMF4
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Show » 83 9.5 No 0
TRIOBP-012 ENSP00000399006
ENST00000428075
Show » 311 34.3 No 0