CHKB

GENE INFORMATION

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Gene name

CHKB (HGNC Symbol)

Synonyms

CHETK, CHKL

Description

choline kinase beta (HGNC Symbol)

Entrez gene summary

Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009]

Chromosome

22 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

51017378 - 51039884

Ensembl

ENSG00000100288 (version 73.37)

Entrez gene

1120

UniProt

Q9Y259 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y259

Antibodypedia

CHKB antibodies
 

PROTEIN VIEW

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CHKB-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHKB-001 ENSP00000384400
ENST00000406938
Q9Y259
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