APOL1

GENE INFORMATION

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Gene name

APOL1 (HGNC Symbol)

Synonyms

APOL

Description

Apolipoprotein L, 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Chromosome

22

Cytoband

q12.3

Chromosome location (bp)

36649056 - 36663576

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100342 (version 75.37)

Entrez gene

8542

UniProt

O14791 (UniProt - Evidence at protein level)

neXtProt

NX_O14791

Antibodypedia

APOL1 antibodies
 

PROTEIN VIEW

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 « 
 
APOL1-001
 
APOL1-003
 
APOL1-008
 
APOL1-009
 
APOL1-011
 
APOL1-012
 
APOL1-013
 
APOL1-014
 
APOL1-201
 
APOL1-202
 
APOL1-203
 
APOL1-204
 
APOL1-205
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOL1-001 ENSP00000380448
ENST00000397278
O14791
Show all »
Show » Show » 398 44 Yes 1
APOL1-003 ENSP00000317674
ENST00000319136
O14791
Show all »
Show » Show » 414 45.9 No 2
APOL1-008 ENSP00000391206
ENST00000422471
B1AH95
Show all »
Show » 141 15 Yes 0
APOL1-009 ENSP00000404525
ENST00000438034
B1AH94
Show all »
Show » Show » 118 13 No 1
APOL1-011 ENSP00000391302
ENST00000427990
B1AH96
Show all »
Show » Show » 160 18.1 Yes 0
APOL1-012 ENSP00000397141
ENST00000439680
F8WB77
Show all »
Show » 123 13.1 Yes 0
APOL1-013 ENSP00000392514
ENST00000433768
B1AH95
Show all »
Show » 141 15 Yes 0
APOL1-014 ENSP00000392857
ENST00000431184
F8WCH3
Show all »
Show » 142 15.1 Yes 0
APOL1-201 ENSP00000216178
ENST00000347595
G8JL88
Show all »
Show » Show » 277 30.9 No 1
APOL1-202 ENSP00000380449
ENST00000397279
O14791
Show all »
Show » Show » 398 44 Yes 1
APOL1-203 ENSP00000411507
ENST00000422706
O14791
Show all »
Show » Show » 398 44 Yes 1
APOL1-204 ENSP00000388477
ENST00000426053
O14791
Show all »
Show » Show » 380 42.2 Yes 0
APOL1-205 ENSP00000397625
ENST00000440669
B1AH95
Show all »
Show » 141 15 Yes 0