MYH9

GENE INFORMATION

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Gene name

MYH9 (HGNC Symbol)

Synonyms

DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA

Description

myosin, heavy chain 9, non-muscle (HGNC Symbol)

Entrez gene summary

This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]

Chromosome

22 (Chromosome progress)

Cytoband

q12.3

Chromosome location (bp)

36677327 - 36784063

Ensembl

ENSG00000100345 (version 73.37)

Entrez gene

4627

UniProt

P35579 (UniProt - Evidence at protein level)

neXtProt

NX_P35579

Antibodypedia

MYH9 antibodies
 

PROTEIN VIEW

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MYH9-001
 
MYH9-002
 
MYH9-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYH9-001 ENSP00000216181
ENST00000216181
P35579
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Show » Show » 1960 226.5 No 0
MYH9-002 ENSP00000384631
ENST00000401701
Q5BKV1
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Show » Show » 218 24.8 No 0
MYH9-015 ENSP00000414852
ENST00000456729
B1AH99
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Show » Show » 103 11.6 No 0