GRAP2

GENE INFORMATION

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Gene name

GRAP2 (HGNC Symbol)

Synonyms

GADS, GRBLG, GrbX, Grf40, Mona

Description

GRB2-related adaptor protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

40297086 - 40369725

Ensembl

ENSG00000100351 (version 73.37)

Entrez gene

9402

UniProt

O75791 (UniProt - Evidence at protein level)

neXtProt

NX_O75791

Antibodypedia

GRAP2 antibodies
 

PROTEIN VIEW

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GRAP2-001
 
GRAP2-003
 
GRAP2-004
 
GRAP2-201
 
GRAP2-202
 
GRAP2-203
 
GRAP2-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRAP2-001 ENSP00000339186
ENST00000344138
O75791
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Show » Show » 330 37.9 No 0
GRAP2-003 ENSP00000385607
ENST00000407075
O75791
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Show » Show » 330 37.9 No 0
GRAP2-004 ENSP00000396355
ENST00000420971
B1AH86
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Show » Show » 97 11 No 0
GRAP2-201 ENSP00000382040
ENST00000399090
B7Z8I3
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Show » Show » 217 24.4 No 0
GRAP2-202 ENSP00000444734
ENST00000540310
F5H548
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Show » Show » 264 30.5 No 0
GRAP2-203 ENSP00000446350
ENST00000543252
F5H1V3
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Show » Show » 278 32.1 No 0
GRAP2-204 ENSP00000442195
ENST00000544756
B7Z8E3
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Show » Show » 258 29.6 No 0