ACO2

GENE INFORMATION

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Gene name

ACO2 (HGNC Symbol)

Synonyms

ACONM

Description

aconitase 2, mitochondrial (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

41865129 - 41924993

Ensembl

ENSG00000100412 (version 73.37)

Entrez gene

50

UniProt

Q99798 (UniProt - Evidence at protein level)

neXtProt

NX_Q99798

Antibodypedia

ACO2 antibodies
 

PROTEIN VIEW

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ACO2-001
 
ACO2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACO2-001 ENSP00000216254
ENST00000216254
Q99798
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Show » Show » 780 85.4 No 0
ACO2-002 ENSP00000379769
ENST00000396512
A2A274
Show all »
Show » Show » 805 87.8 No 0