FKBP3

GENE INFORMATION

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Gene name

FKBP3 (HGNC Symbol)

Synonyms

FKBP-25, PPIase

Description

FK506 binding protein 3, 25kDa (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]

Chromosome

14 (Chromosome progress)

Cytoband

q21.2

Chromosome location (bp)

45584803 - 45604522

Ensembl

ENSG00000100442 (version 73.37)

Entrez gene

2287

UniProt

Q00688 (UniProt - Evidence at protein level)

neXtProt

NX_Q00688

Antibodypedia

FKBP3 antibodies
 

PROTEIN VIEW

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FKBP3-001
 
FKBP3-002
 
FKBP3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FKBP3-001 ENSP00000216330
ENST00000216330
Q00688
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Show » Show » 224 25.2 No 0
FKBP3-002 ENSP00000452322
ENST00000557324
G3V5F2
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65 7.2 No 0
FKBP3-201 ENSP00000379374
ENST00000396062
Q00688
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Show » Show » 224 25.2 No 0