NIN

GENERAL INFORMATION

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Gene name

NIN

Gene description

Ninein (GSK3B interacting protein)

Protein class

Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

11
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Respiratory epithelia, gastrointestinal tract, renal tubules, glandular cells of cervix, myocytes, salivary gland and cells of male genital tract showed moderate cytoplasmic positivity. Urothelium, decidual cells and lymphoid cells showed distinct dot-like positivity. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA005939
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

NIN

Synonyms

Description

Ninein (GSK3B interacting protein) (HGNC Symbol)

Entrez gene summary

This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q22.1

Chromosome location (bp)

50719763 - 50831121

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100503 (version 78.38)

Entrez gene

51199

UniProt

Q8N4C6 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N4C6

Antibodypedia

NIN antibodies


PROTEIN BROWSER

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ENST00000245441
 
ENST00000324330
 
ENST00000382041
 
ENST00000382043
 
ENST00000389869
 
ENST00000453196
 
ENST00000453401
 
ENST00000486950
 
ENST00000496749
 
ENST00000530853
 
ENST00000530997
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NIN-004 ENSP00000431826
ENST00000496749
E9PJH9
Show all »
Show » Show » 101 11.6 No 0
NIN-008 ENSP00000398641
ENST00000453401
H7C162
Show all »
Show » Show » 396 45.3 No 0
NIN-010 ENSP00000371474
ENST00000382043
Q8N4C6
Show all »
Show » Show » 1377 160.1 No 0
NIN-012 ENSP00000473530
ENST00000486950
Show » 116 13.1 No 0
NIN-016 ENSP00000371472
ENST00000382041
Q8N4C6
Show all »
Show » Show » 2090 243.2 No 0
NIN-017 ENSP00000436092
ENST00000530997
Q8N4C6
Show all »
Show » Show » 2133 248.2 No 0
NIN-018 ENSP00000433717
ENST00000530853
Show » 1537 179.4 No 0
NIN-019 ENSP00000374519
ENST00000389869
Show » 1581 184.5 No 0
NIN-201 ENSP00000245441
ENST00000245441
Q8N4C6
Show all »
Show » Show » 2133 248.2 No 0
NIN-202 ENSP00000324210
ENST00000324330
Q8N4C6
Show all »
Show » Show » 1377 160.1 No 0
NIN-203 ENSP00000412391
ENST00000453196
C9J066
Show all »
Show » Show » 2046 238.2 No 0