ATP6V1D

GENE INFORMATION

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Gene name

ATP6V1D (HGNC Symbol)

Synonyms

ATP6M, VATD, VMA8

Description

ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D (HGNC Symbol)

Entrez gene summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c"", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008]

Chromosome

14 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

67761088 - 67826982

Ensembl

ENSG00000100554 (version 73.37)

Entrez gene

51382

UniProt

Q9Y5K8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5K8

Antibodypedia

ATP6V1D antibodies
 

PROTEIN VIEW

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 « 
 
ATP6V1D-001
 
ATP6V1D-002
 
ATP6V1D-004
 
ATP6V1D-005
 
ATP6V1D-006
 
ATP6V1D-009
 
ATP6V1D-010
 
ATP6V1D-011
 
ATP6V1D-013
 
ATP6V1D-014
 
ATP6V1D-015
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V1D-001 ENSP00000216442
ENST00000216442
Q9Y5K8
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Show » 247 28.3 No 0
ATP6V1D-002 ENSP00000450885
ENST00000555474
G3V2V6
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Show » 148 17.4 No 0
ATP6V1D-004 ENSP00000451167
ENST00000554087
Q9Y5K8
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Show » 247 28.3 No 0
ATP6V1D-005 ENSP00000451031
ENST00000555012
G3V341
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Show » 72 8.2 No 0
ATP6V1D-006 ENSP00000452492
ENST00000553687
G3V5S7
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Show » 59 6.6 No 0
ATP6V1D-009 ENSP00000451422
ENST00000556058
G3V3T8
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Show » 86 9.8 No 0
ATP6V1D-010 ENSP00000450834
ENST00000553408
H0YJ55
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Show » 44 4.7 No 0
ATP6V1D-011 ENSP00000451564
ENST00000555625
H0YJH8
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Show » 153 17.7 No 0
ATP6V1D-013 ENSP00000452192
ENST00000554236
G3V559
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Show » 179 19.9 No 0
ATP6V1D-014 ENSP00000450841
ENST00000555431
G3V2S6
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Show » 192 21.9 No 0
ATP6V1D-015 ENSP00000452029
ENST00000555723
H0YJS0
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Show » 119 13.2 No 0