PSMA3

GENE INFORMATION

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Gene name

PSMA3 (HGNC Symbol)

Synonyms

HC8

Description

proteasome (prosome, macropain) subunit, alpha type, 3 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

14 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

58711549 - 58738730

Ensembl

ENSG00000100567 (version 73.37)

Entrez gene

5684

UniProt

P25788 (UniProt - Evidence at protein level)

neXtProt

NX_P25788

Antibodypedia

PSMA3 antibodies
 

PROTEIN VIEW

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PSMA3-001
 
PSMA3-002
 
PSMA3-007
 
PSMA3-011
 
PSMA3-012
 
PSMA3-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMA3-001 ENSP00000216455
ENST00000216455
P25788
Show all »
Show » Show » 255 28.4 No 0
PSMA3-002 ENSP00000390491
ENST00000412908
P25788
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Show » Show » 248 27.6 No 0
PSMA3-007 ENSP00000450573
ENST00000553677
H0YJ03
Show all »
Show » 83 9.7 No 0
PSMA3-011 ENSP00000452437
ENST00000555931
G3V5N4
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Show » 54 6.2 No 0
PSMA3-012 ENSP00000451461
ENST00000557087
G3V3W4
Show all »
Show » 36 3.9 No 0
PSMA3-013 ENSP00000452056
ENST00000557508
G3V4X5
Show all »
Show » 180 20.3 No 0