Fields »

SUBCELLULAR LOCATION

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Main location(s)

Nucleus, Nucleoli, Nuclear membrane

Additional location(s)

 

Staining summary

Localized to the nucleus, nucleoli and nuclear membrane.

Reliability (APE)

Low

Antibodies in assay

HPA030673, HPA030677
 

Antibody HPA030673

 

Antibody HPA030677

 

         Cell line A-431

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Location(s)

Nucleus, Nucleoli, Nuclear membrane Nucleus but not nucleoli 

Staining characteristics

  

Staining intensity

Strong Moderate 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Nucleus, Nucleoli, Nuclear membrane, Cytoplasm Nucleus but not nucleoli 

Staining characteristics

  

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Nucleus, Nucleoli, Nuclear membrane Nucleus but not nucleoli 

Staining characteristics

  

Staining intensity

Strong Strong 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in nucleus, nucleoli & nuclear membrane.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.
 

Summary

Staining of nucleus and nuclear membrane in all three cell lines. Additional staining of cytoplasm in U-2 OS.   Staining of nucleus in all three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Nuclear membrane
Nucleoli
Nucleus