ALKBH1

GENERAL INFORMATION

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Gene name

ALKBH1

Gene description

AlkB, alkylation repair homolog 1 (E. coli)

Protein class

Enzymes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic and nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA044087
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ALKBH1 (HGNC Symbol)

Synonyms

ABH, alkB, ALKBH, hABH

Description

AlkB, alkylation repair homolog 1 (E. coli) (HGNC Symbol)

Entrez gene summary

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q24.3

Chromosome location (bp)

77672404 - 77708020

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100601 (version 78.38)

Entrez gene

8846

UniProt

Q13686 (UniProt - Evidence at protein level)

neXtProt

NX_Q13686

Antibodypedia

ALKBH1 antibodies


PROTEIN BROWSER

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ENST00000216489
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALKBH1-001 ENSP00000216489
ENST00000216489
Q13686
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