CHGA

GENE INFORMATION

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Gene name

CHGA

Synonyms

Description

Chromogranin A (parathyroid secretory protein 1) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q32.12

Chromosome location (bp)

93389425 - 93401638

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100604 (version 75.37)

Entrez gene

1113

UniProt

P10645 (UniProt - Evidence at protein level)

neXtProt

NX_P10645

Antibodypedia

CHGA antibodies
 

PROTEIN VIEW

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CHGA-001
 
CHGA-003
 
CHGA-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHGA-001 ENSP00000216492
ENST00000216492
P10645
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Show » Show » 457 50.7 Yes 0
CHGA-003 ENSP00000334023
ENST00000334654
G5E968
Show all »
Show » Show » 306 34.3 Yes 0
CHGA-004 ENSP00000450801
ENST00000556076
G3V2Q7
Show all »
Show » Show » 38 4 Yes 0