BDKRB1

GENE INFORMATION

? »

Gene name

BDKRB1 (HGNC Symbol)

Synonyms

B1BKR, BKR1, bradyb1

Description

bradykinin receptor B1 (HGNC Symbol)

Entrez gene summary

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

14 (Chromosome progress)

Cytoband

q32.2

Chromosome location (bp)

96722161 - 96735304

Ensembl

ENSG00000100739 (version 73.37)

Entrez gene

623

UniProt

P46663 (UniProt - Evidence at protein level)

neXtProt

NX_P46663

Antibodypedia

BDKRB1 antibodies
 

PROTEIN VIEW

? »
 
 
 
BDKRB1-001
 
BDKRB1-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BDKRB1-001 ENSP00000216629
ENST00000216629
P46663
Show all »
Show » Show » 353 40.5 No 7
BDKRB1-002 ENSP00000452064
ENST00000553356
G3V4Y2
Show all »
Show » Show » 284 32.4 No 6