ACIN1

GENE INFORMATION

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Gene name

ACIN1 (HGNC Symbol)

Synonyms

ACINUS, fSAP152, KIAA0670

Description

apoptotic chromatin condensation inducer 1 (HGNC Symbol)

Entrez gene summary

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

14 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

23527773 - 23564823

Ensembl

ENSG00000100813 (version 73.37)

Entrez gene

22985

UniProt

Q9UKV3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKV3

Antibodypedia

ACIN1 antibodies
 

PROTEIN VIEW

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ACIN1-001
 
ACIN1-002
 
ACIN1-003
 
ACIN1-004
 
ACIN1-006
 
ACIN1-007
 
ACIN1-014
 
ACIN1-022
 
ACIN1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACIN1-001 ENSP00000350073
ENST00000357481
Q9UKV3
Show all »
Show » Show » 583 67.6 No 0
ACIN1-002 ENSP00000345541
ENST00000338631
Q9UKV3
Show all »
Show » Show » 614 70.9 No 0
ACIN1-003 ENSP00000262710
ENST00000262710
Q9UKV3
Show all »
Show » Show » 1341 151.9 No 0
ACIN1-004 ENSP00000380502
ENST00000397341
Q9UKV3
Show all »
Show » Show » 583 67.6 No 0
ACIN1-006 ENSP00000451328
ENST00000555053
Q9UKV3
Show all »
Show » Show » 1328 150.6 No 0
ACIN1-007 ENSP00000451138
ENST00000557515
G3V3B0
Show all »
Show » 582 67.5 No 0
ACIN1-014 ENSP00000451410
ENST00000555566
G3V3T3
Show all »
194 21.1 No 0
ACIN1-022 ENSP00000474349
ENST00000605057
Show » 1283 145.4 No 0
ACIN1-201 ENSP00000405677
ENST00000457657
E7EQT4
Show all »
Show » 1301 147.4 No 0