PLTP

GENERAL INFORMATION

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Gene name

PLTP

Gene description

Phospholipid transfer protein

Protein class

Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Transporters

Predicted localization

Intracellular,Secreted

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal tissues showed moderate cytoplasmic staining. Gall bladder, rectum and Leydig cells displayed strong positivity. Plasma were distinctly stained. Bile duct cells, cells in glomeruli, glial cells, ganglie smooth and skeletal muscle were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB032873
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PLTP (HGNC Symbol)

Synonyms

BPIFE

Description

Phospholipid transfer protein (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

45898621 - 45912155

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100979 (version 78.38)

Entrez gene

5360

UniProt

P55058 (UniProt - Evidence at protein level)

neXtProt

NX_P55058

Antibodypedia

PLTP antibodies


PROTEIN BROWSER

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ENST00000354050
 
ENST00000372420
 
ENST00000372431
 
ENST00000420868
 
ENST00000477313
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLTP-001 ENSP00000361508
ENST00000372431
P55058
Show all »
Show » Show » 493 54.7 Yes 0
PLTP-002 ENSP00000361497
ENST00000372420
P55058
Show all »
Show » Show » 405 44.8 No 0
PLTP-003 ENSP00000335290
ENST00000354050
P55058
Show all »
Show » Show » 441 49.3 Yes 0
PLTP-004 ENSP00000411671
ENST00000420868
P55058
Show all »
Show » Show » 398 44.1 Yes 0
PLTP-005 ENSP00000417138
ENST00000477313
P55058
Show all »
Show » Show » 493 54.7 Yes 0