GSS

GENE INFORMATION

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Gene name

GSS

Synonyms

Description

glutathione synthetase (HGNC Symbol)

Entrez gene summary

Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q11.22

Chromosome location (bp)

33516236 - 33543620

Ensembl

ENSG00000100983 (version 73.37)

Entrez gene

2937

UniProt

P48637 (UniProt - Evidence at protein level)

neXtProt

NX_P48637

Antibodypedia

GSS antibodies
 

PROTEIN VIEW

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GSS-001
 
GSS-201
 
GSS-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GSS-001 ENSP00000216951
ENST00000216951
P48637
Show all »
Show » Show » 474 52.4 No 0
GSS-201 ENSP00000407517
ENST00000451957
B6F210
Show all »
Show » 363 40.3 No 0
GSS-202 ENSP00000439744
ENST00000541098
B7Z514
Show all »
Show » 346 38.2 No 0