PTK6

GENE INFORMATION

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Gene name

PTK6 (HGNC Symbol)

Synonyms

BRK

Description

protein tyrosine kinase 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Chromosome

20 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

62159778 - 62168723

Ensembl

ENSG00000101213 (version 73.37)

Entrez gene

5753

UniProt

Q13882 (UniProt - Evidence at protein level)

neXtProt

NX_Q13882

Antibodypedia

PTK6 antibodies
 

PROTEIN VIEW

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PTK6-001
 
PTK6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTK6-001 ENSP00000217185
ENST00000217185
Q13882
Show all »
Show » Show » 451 51.8 No 0
PTK6-201 ENSP00000442460
ENST00000542869
Q13882
Show all »
Show » Show » 350 40.6 No 0