TRIB3

GENE INFORMATION

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Gene name

TRIB3 (HGNC Symbol)

Synonyms

C20orf97, dJ1103G7.3, TRB3

Description

Tribbles pseudokinase 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

361261 - 378203

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101255 (version 75.37)

Entrez gene

57761

UniProt

Q96RU7 (UniProt - Evidence at protein level)

neXtProt

NX_Q96RU7

Antibodypedia

TRIB3 antibodies
 

PROTEIN VIEW

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TRIB3-001
 
TRIB3-003
 
TRIB3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRIB3-001 ENSP00000217233
ENST00000217233
Q96RU7
Show all »
Show » Show » 358 39.6 No 0
TRIB3-003 ENSP00000391873
ENST00000449710
B0QYQ2
Show all »
Show » Show » 271 29.9 No 0
TRIB3-201 ENSP00000415416
ENST00000422053
J3KR25
Show all »
Show » Show » 385 42.8 No 0