HCK

GENE INFORMATION

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Gene name

HCK (HGNC Symbol)

Synonyms

JTK9

Description

hemopoietic cell kinase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]

Chromosome

20 (Chromosome progress)

Cytoband

q11.21

Chromosome location (bp)

30639991 - 30689659

Ensembl

ENSG00000101336 (version 73.37)

Entrez gene

3055

UniProt

P08631 (UniProt - Evidence at protein level)

neXtProt

NX_P08631

Antibodypedia

HCK antibodies
 

PROTEIN VIEW

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HCK-001
 
HCK-002
 
HCK-004
 
HCK-005
 
HCK-006
 
HCK-007
 
HCK-201
 
HCK-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HCK-001 ENSP00000365012
ENST00000375852
J3KPD6
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Show » Show » 526 59.6 No 0
HCK-002 ENSP00000365022
ENST00000375862
H0Y3C5
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Show » Show » 525 59.5 No 0
HCK-004 ENSP00000420457
ENST00000486475
H7C5P9
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61 6.9 No 0
HCK-005 ENSP00000262651
ENST00000262651
H7BXG4
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41 4.6 No 0
HCK-006 ENSP00000429848
ENST00000520553
P08631
Show all »
Show » Show » 505 57.3 No 0
HCK-007 ENSP00000427757
ENST00000518730
P08631
Show all »
Show » Show » 504 57.2 No 0
HCK-201 ENSP00000444986
ENST00000534862
A8K4G3
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Show » Show » 506 57.4 No 0
HCK-202 ENSP00000441169
ENST00000538448
P08631
Show all »
Show » Show » 505 57.3 No 0