SAMHD1

GENE INFORMATION

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Gene name

SAMHD1 (HGNC Symbol)

Synonyms

AGS5, HDDC1, Mg11, MOP-5, SBBI88

Description

SAM domain and HD domain 1 (HGNC Symbol)

Entrez gene summary

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]

Chromosome

20

Cytoband

q11.23

Chromosome location (bp)

35518632 - 35580246

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101347 (version 75.37)

Entrez gene

25939

UniProt

Q9Y3Z3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y3Z3

Antibodypedia

SAMHD1 antibodies
 

PROTEIN VIEW

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SAMHD1-001
 
SAMHD1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SAMHD1-001 ENSP00000262878
ENST00000262878
Q9Y3Z3
Show all »
Show » Show » 626 72.2 No 0
SAMHD1-201 ENSP00000362798
ENST00000373694
A6NDZ3
Show all »
Show » Show » 170 20.1 No 0