WFDC2

GENE INFORMATION

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Gene name

WFDC2 (HGNC Symbol)

Synonyms

dJ461P17.6, EDDM4, HE4, WAP5

Description

WAP four-disulfide core domain 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q13.12

Chromosome location (bp)

44098346 - 44110172

Ensembl

ENSG00000101443 (version 73.37)

Entrez gene

10406

UniProt

Q14508 (UniProt - Evidence at protein level)

neXtProt

NX_Q14508

Antibodypedia

WFDC2 antibodies
 

PROTEIN VIEW

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WFDC2-002
 
WFDC2-003
 
WFDC2-004
 
WFDC2-005
 
WFDC2-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WFDC2-002 ENSP00000361761
ENST00000372676
Q14508
Show all »
Show » Show » 124 13 Yes 0
WFDC2-003 ENSP00000217425
ENST00000217425
Q14508
Show all »
Show » Show » 102 11 Yes 0
WFDC2-004 ENSP00000404760
ENST00000447118
A8K2M3
Show all »
Show » Show » 79 8.1 Yes 0
WFDC2-005 ENSP00000340215
ENST00000339946
Q14508
Show all »
Show » Show » 76 8.1 Yes 0
WFDC2-006 ENSP00000342890
ENST00000342873
Q14508
Show all »
Show » Show » 73 8.1 No 0