AHCY

GENE INFORMATION

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Gene name

AHCY (HGNC Symbol)

Synonyms

SAHH

Description

adenosylhomocysteinase (HGNC Symbol)

Entrez gene summary

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Chromosome

20 (Chromosome progress)

Cytoband

q11.22

Chromosome location (bp)

32868074 - 32899608

Ensembl

ENSG00000101444 (version 73.37)

Entrez gene

191

UniProt

P23526 (UniProt - Evidence at protein level)

neXtProt

NX_P23526

Antibodypedia

AHCY antibodies
 

PROTEIN VIEW

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AHCY-002
 
AHCY-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AHCY-002 ENSP00000217426
ENST00000217426
P23526
Show all »
Show » Show » 432 47.7 No 0
AHCY-006 ENSP00000442820
ENST00000538132
P23526
Show all »
Show » Show » 404 44.7 No 0