LPIN2

GENERAL INFORMATION

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Gene name

LPIN2

Gene description

Lipin 2

Protein class

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA017857 , HPA030550 , CAB015223
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

LPIN2 (HGNC Symbol)

Synonyms

KIAA0249

Description

Lipin 2 (HGNC Symbol)

Entrez gene summary

Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

p11.31

Chromosome location (bp)

2916994 - 3013315

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101577 (version 78.38)

Entrez gene

9663

UniProt

Q92539 (UniProt - Evidence at protein level)

neXtProt

NX_Q92539

Antibodypedia

LPIN2 antibodies


PROTEIN BROWSER

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ENST00000261596
 
ENST00000584294
 
ENST00000584915
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LPIN2-001 ENSP00000261596
ENST00000261596
Q92539
Show all »
Show » Show » 896 99.4 No 0
LPIN2-002 ENSP00000463026
ENST00000584294
J3KTK1
Show all »
Show » Show » 233 25.6 No 0
LPIN2-003 ENSP00000463810
ENST00000584915
J3QQN0
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Show » Show » 129 14.3 No 0