MIB1

GENE INFORMATION

? »

Gene name

MIB1 (HGNC Symbol)

Synonyms

DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6

Description

mindbomb E3 ubiquitin protein ligase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]

Chromosome

18 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

19284918 - 19450918

Ensembl

ENSG00000101752 (version 73.37)

Entrez gene

57534

UniProt

Q86YT6 (UniProt - Evidence at protein level)

neXtProt

NX_Q86YT6

Antibodypedia

MIB1 antibodies
 

PROTEIN VIEW

? »
 
 
 
MIB1-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MIB1-001 ENSP00000261537
ENST00000261537
Q86YT6
Show all »
Show » 1006 110.1 No 0