ATG4A

GENE INFORMATION

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Gene name

ATG4A (HGNC Symbol)

Synonyms

APG4A, AUTL2

Description

autophagy related 4A, cysteine peptidase (HGNC Symbol)

Entrez gene summary

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

q22.3

Chromosome location (bp)

107334898 - 107397901

Ensembl

ENSG00000101844 (version 73.37)

Entrez gene

115201

UniProt

Q8WYN0 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WYN0

Antibodypedia

ATG4A antibodies
 

PROTEIN VIEW

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ATG4A-001
 
ATG4A-002
 
ATG4A-003
 
ATG4A-004
 
ATG4A-005
 
ATG4A-006
 
ATG4A-201
 
ATG4A-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATG4A-001 ENSP00000361306
ENST00000372232
Q8WYN0
Show all »
Show » Show » 398 45.4 No 0
ATG4A-002 ENSP00000298131
ENST00000345734
Q8WYN0
Show all »
Show » Show » 336 38.6 No 0
ATG4A-003 ENSP00000361320
ENST00000372246
F8W7J2
Show all »
47 5.8 No 0
ATG4A-004 ENSP00000341833
ENST00000343524
G5E979
Show all »
Show » Show » 231 26.5 No 0
ATG4A-005 ENSP00000378354
ENST00000394892
312 35.1 No 0
ATG4A-006 ENSP00000416218
ENST00000457035
Q8WYN0
Show all »
Show » Show » 202 22.8 No 0
ATG4A-201 ENSP00000361328
ENST00000372254
Q8WYN0
Show all »
Show » Show » 374 42.5 No 0
ATG4A-202 ENSP00000438936
ENST00000545696
F5H3G3
Show all »
Show » 259 29.8 No 0