GUCY2F

GENERAL INFORMATION

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Gene name

GUCY2F

Gene description

Guanylate cyclase 2F, retinal

Protein class

Enzymes
Plasma proteins
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Not detected
GTEx:Not detected

Protein evidence

Evidence at protein level

Protein localization

External data suggests expression in retina. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

External characterization data supports antibody staining pattern while RNA data does not. Pending additional tissue.

Data reliability

Uncertain based on 2 antibodies.
HPA000734 , HPA027473
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Not detected

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

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Gene name

GUCY2F (HGNC Symbol)

Synonyms

CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2

Description

Guanylate cyclase 2F, retinal (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008]

Chromosome

X

Cytoband

Chromosome location (bp)

109372906 - 109482072

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101890 (version 78.38)

Entrez gene

2986

UniProt

P51841 (UniProt - Evidence at transcript level)

neXtProt

NX_P51841

Antibodypedia

GUCY2F antibodies


PROTEIN BROWSER

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ENST00000218006
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GUCY2F-001 ENSP00000218006
ENST00000218006
P51841
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