ATP1B4

GENERAL INFORMATION

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Gene name

ATP1B4

Gene description

ATPase, Na+/K+ transporting, beta 4 polypeptide

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (skeletal muscle)
GTEx:Tissue enriched (skeletal muscle)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (skeletal muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (skeletal muscle)

Organ

Expression



GENE INFORMATION

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Gene name

ATP1B4

Synonyms

Description

ATPase, Na+/K+ transporting, beta 4 polypeptide (HGNC Symbol)

Entrez gene summary

This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Chromosome

X

Cytoband

q24

Chromosome location (bp)

120362085 - 120383249

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101892 (version 78.38)

Entrez gene

23439

UniProt

Q9UN42 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UN42

Antibodypedia

ATP1B4 antibodies


PROTEIN BROWSER

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ENST00000218008
 
ENST00000361319
 
ENST00000539306
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP1B4-001 ENSP00000218008
ENST00000218008
Q9UN42
Show all »
Show » Show » 357 41.6 No 1
ATP1B4-002 ENSP00000355346
ENST00000361319
Q9UN42
Show all »
Show » Show » 353 41.1 No 1
ATP1B4-201 ENSP00000443334
ENST00000539306
B7ZKW0
Show all »
Show » Show » 314 36.7 No 0