CCDC22

GENE INFORMATION

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Gene name

CCDC22 (HGNC Symbol)

Synonyms

CXorf37, JM1

Description

coiled-coil domain containing 22 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013]

Chromosome

X (Chromosome progress)

Cytoband

p11.23

Chromosome location (bp)

49091927 - 49106987

Ensembl

ENSG00000101997 (version 73.37)

Entrez gene

28952

UniProt

O60826 (UniProt - Evidence at protein level)

neXtProt

NX_O60826

Antibodypedia

CCDC22 antibodies
 

PROTEIN VIEW

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CCDC22-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCDC22-001 ENSP00000365401
ENST00000376227
O60826
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