BMX

GENE INFORMATION

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Gene name

BMX (HGNC Symbol)

Synonyms

ETK, PSCTK3

Description

BMX non-receptor tyrosine kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009]

Chromosome

X (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

15482369 - 15574652

Ensembl

ENSG00000102010 (version 73.37)

Entrez gene

660

UniProt

P51813 (UniProt - Evidence at protein level)

neXtProt

NX_P51813

Antibodypedia

BMX antibodies
 

PROTEIN VIEW

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BMX-001
 
BMX-005
 
BMX-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BMX-001 ENSP00000340082
ENST00000342014
P51813
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Show » Show » 675 78 No 0
BMX-005 ENSP00000350224
ENST00000357607
P51813
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Show » Show » 675 78 No 0
BMX-006 ENSP00000308774
ENST00000348343
P51813
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Show » Show » 675 78 No 0