PQBP1

GENERAL INFORMATION

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Gene name

PQBP1

Gene description

Polyglutamine binding protein 1

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA001880
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PQBP1 (HGNC Symbol)

Synonyms

MRX2, MRX55, MRXS8, RENS1, SHS

Description

Polyglutamine binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked mental retardation. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]

Chromosome

X

Cytoband

p11.23

Chromosome location (bp)

48897912 - 48903143

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102103 (version 78.38)

Entrez gene

10084

UniProt

O60828 (UniProt - Evidence at protein level)

neXtProt

NX_O60828

Antibodypedia

PQBP1 antibodies


PROTEIN BROWSER

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ENST00000218224
 
ENST00000247140
 
ENST00000376563
 
ENST00000376566
 
ENST00000396763
 
ENST00000443648
 
ENST00000447146
 
ENST00000456306
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PQBP1-001 ENSP00000391759
ENST00000447146
O60828
Show all »
Show » Show » 265 30.5 No 0
PQBP1-002 ENSP00000247140
ENST00000247140
O60828
Show all »
Show » Show » 170 18.8 No 0
PQBP1-007 ENSP00000393013
ENST00000456306
Show » Show » 150 16.5 No 0
PQBP1-011 ENSP00000414861
ENST00000443648
C9JQA1
Show all »
Show » Show » 213 24.9 No 0
PQBP1-201 ENSP00000218224
ENST00000218224
O60828
Show all »
Show » Show » 265 30.5 No 0
PQBP1-202 ENSP00000365747
ENST00000376563
O60828
Show all »
Show » Show » 265 30.5 No 0
PQBP1-203 ENSP00000365750
ENST00000376566
O60828
Show all »
Show » Show » 170 18.8 No 0
PQBP1-204 ENSP00000379985
ENST00000396763
O60828
Show all »
Show » Show » 265 30.5 No 0