CD40LG

GENE INFORMATION

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Gene name

CD40LG (HGNC Symbol)

Synonyms

CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP

Description

CD40 ligand (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

135730352 - 135742549

Ensembl

ENSG00000102245 (version 73.37)

Entrez gene

959

UniProt

P29965 (UniProt - Evidence at protein level)

neXtProt

NX_P29965

Antibodypedia

CD40LG antibodies
 

PROTEIN VIEW

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CD40LG-001
 
CD40LG-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD40LG-001 ENSP00000359663
ENST00000370629
P29965
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Show » Show » 261 29.3 No 1
CD40LG-002 ENSP00000359662
ENST00000370628
Q3L8U2
Show all »
Show » Show » 240 27.2 No 1