STK24

GENE INFORMATION

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Gene name

STK24 (HGNC Symbol)

Synonyms

MST-3, MST3, MST3B, STE20, STK3

Description

serine/threonine kinase 24 (HGNC Symbol)

Entrez gene summary

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM, Mar 2008]

Chromosome

13 (Chromosome progress)

Cytoband

q32.2

Chromosome location (bp)

99102455 - 99230194

Ensembl

ENSG00000102572 (version 73.37)

Entrez gene

8428

UniProt

Q9Y6E0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6E0

Antibodypedia

STK24 antibodies
 

PROTEIN VIEW

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STK24-001
 
STK24-002
 
STK24-003
 
STK24-005
 
STK24-006
 
STK24-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STK24-001 ENSP00000380651
ENST00000397517
Q9Y6E0
Show all »
Show » Show » 431 47.9 No 0
STK24-002 ENSP00000365730
ENST00000376547
Q9Y6E0
Show all »
Show » Show » 443 49.3 No 0
STK24-003 ENSP00000402764
ENST00000444574
Q5JV99
Show all »
Show » 369 40.8 No 0
STK24-005 ENSP00000365737
ENST00000376554
Q5JV98
Show all »
Show » 209 23.1 No 0
STK24-006 ENSP00000402810
ENST00000418038
Q5JV99
Show all »
142 15.8 No 0
STK24-201 ENSP00000442539
ENST00000539966
B4DR80
Show all »
Show » 412 45.8 No 0