ARHGEF7

GENE INFORMATION

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Gene name

ARHGEF7 (HGNC Symbol)

Synonyms

BETA-PIX, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB

Description

Rho guanine nucleotide exchange factor (GEF) 7 (HGNC Symbol)

Entrez gene summary

Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

13 (Chromosome progress)

Cytoband

q34

Chromosome location (bp)

111766906 - 111958084

Ensembl

ENSG00000102606 (version 73.37)

Entrez gene

8874

UniProt

Q14155 (UniProt - Evidence at protein level)

neXtProt

NX_Q14155

Antibodypedia

ARHGEF7 antibodies
 

PROTEIN VIEW

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ARHGEF7-001
 
ARHGEF7-003
 
ARHGEF7-004
 
ARHGEF7-005
 
ARHGEF7-007
 
ARHGEF7-008
 
ARHGEF7-009
 
ARHGEF7-011
 
ARHGEF7-012
 
ARHGEF7-013
 
ARHGEF7-015
 
ARHGEF7-016
 
ARHGEF7-201
 
ARHGEF7-202
 
ARHGEF7-203
 
ARHGEF7-204
 
ARHGEF7-205
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF7-001 ENSP00000218789
ENST00000218789
B1ALK7
Show all »
Show » Show » 705 79.8 No 0
ARHGEF7-003 ENSP00000406732
ENST00000449979
B1ANY6
Show all »
Show » Show » 66 7.6 No 0
ARHGEF7-004 ENSP00000397068
ENST00000426073
Q14155
Show all »
Show » Show » 646 73.1 No 0
ARHGEF7-005 ENSP00000364875
ENST00000375723
Q14155
Show all »
Show » Show » 625 70.4 No 0
ARHGEF7-007 ENSP00000364888
ENST00000375736
Q14155
Show all »
Show » Show » 646 73.1 No 0
ARHGEF7-008 ENSP00000325994
ENST00000317133
Q14155
Show all »
Show » Show » 782 87.8 No 0
ARHGEF7-009 ENSP00000389890
ENST00000426768
E7ENL8
Show all »
Show » Show » 143 16 No 0
ARHGEF7-011 ENSP00000417596
ENST00000478679
E9PDQ5
Show all »
Show » 547 61.6 No 0
ARHGEF7-012 ENSP00000418235
ENST00000469877
E7EU80
Show all »
Show » Show » 151 16.4 No 0
ARHGEF7-013 ENSP00000418067
ENST00000466143
E7EUY6
Show all »
Show » Show » 447 50.5 No 0
ARHGEF7-015 ENSP00000418043
ENST00000491775
C9JAD7
Show all »
Show » Show » 39 4.5 No 0
ARHGEF7-016 ENSP00000420592
ENST00000467053
C9JDI6
Show all »
Show » Show » 61 7.1 No 0
ARHGEF7-201 ENSP00000359657
ENST00000370623
Q14155
Show all »
Show » Show » 731 82.6 No 0
ARHGEF7-202 ENSP00000364889
ENST00000375737
B7Z6G2
Show all »
Show » Show » 721 81.4 No 0
ARHGEF7-203 ENSP00000364891
ENST00000375739
Q14155
Show all »
Show » Show » 753 84.5 No 0
ARHGEF7-204 ENSP00000364893
ENST00000375741
Q14155
Show all »
Show » Show » 803 90 No 0
ARHGEF7-205 ENSP00000445384
ENST00000544132
B7Z6D9
Show all »
Show » 181 20.2 No 0