MAPK3

GENE INFORMATION

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Gene name

MAPK3 (HGNC Symbol)

Synonyms

ERK1, p44erk1, p44mapk, PRKM3

Description

Mitogen-activated protein kinase 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

p11.2

Chromosome location (bp)

30114105 - 30123506

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102882 (version 78.38)

Entrez gene

5595

UniProt

P27361 (UniProt - Evidence at protein level)

neXtProt

NX_P27361

Antibodypedia

MAPK3 antibodies
 

PROTEIN VIEW

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MAPK3-001
 
MAPK3-003
 
MAPK3-004
 
MAPK3-006
 
MAPK3-007
 
MAPK3-009
 
MAPK3-011
 
MAPK3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAPK3-001 ENSP00000263025
ENST00000263025
P27361
Show all »
Show » Show » 379 43.1 No 0
MAPK3-003 ENSP00000432742
ENST00000484663
B3KR49
Show all »
Show » Show » 265 30.6 No 0
MAPK3-004 ENSP00000378628
ENST00000395202
P27361
Show all »
Show » Show » 335 38.3 No 0
MAPK3-006 ENSP00000378625
ENST00000395199
P27361
Show all »
Show » Show » 357 40.1 No 0
MAPK3-007 ENSP00000433639
ENST00000481230
H0YDH9
Show all »
Show » Show » 87 10.2 No 0
MAPK3-009 ENSP00000432292
ENST00000478356
E9PRH7
Show all »
Show » Show » 136 15.8 No 0
MAPK3-011 ENSP00000378626
ENST00000395200
E9PBK7
Show all »
Show » Show » 311 36 No 0
MAPK3-201 ENSP00000327293
ENST00000322266
P27361
Show all »
Show » Show » 335 38.3 No 0