ABCC1

GENE INFORMATION

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Gene name

ABCC1 (HGNC Symbol)

Synonyms

GS-X, MRP, MRP1

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]

Chromosome

16 (Chromosome progress)

Cytoband

p13.11

Chromosome location (bp)

16043434 - 16236931

Ensembl

ENSG00000103222 (version 73.37)

Entrez gene

4363

UniProt

P33527 (UniProt - Evidence at protein level)

neXtProt

NX_P33527

Antibodypedia

ABCC1 antibodies
 

PROTEIN VIEW

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ABCC1-001
 
ABCC1-005
 
ABCC1-007
 
ABCC1-201
 
ABCC1-202
 
ABCC1-203
 
ABCC1-204
 
ABCC1-205
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC1-001 ENSP00000382342
ENST00000399410
P33527
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Show » Show » 1531 171.6 No >9
ABCC1-005 ENSP00000459693
ENST00000572053
I3L2H9
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22 2.5 No 0
ABCC1-007 ENSP00000461615
ENST00000572882
Q9BV39
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Show » Show » 1440 160.4 No >9
ABCC1-201 ENSP00000263014
ENST00000345148
P33527
Show all »
Show » Show » 1466 164.3 No >9
ABCC1-202 ENSP00000263019
ENST00000346370
P33527
Show all »
Show » Show » 1475 165.6 No >9
ABCC1-203 ENSP00000263016
ENST00000349029
P33527
Show all »
Show » Show » 1416 158.9 No >9
ABCC1-204 ENSP00000263017
ENST00000351154
P33527
Show all »
Show » Show » 1472 165 No >9
ABCC1-205 ENSP00000382340
ENST00000399408
P33527
Show all »
Show » Show » 1541 172.6 No >9