EEF2K

GENE INFORMATION

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Gene name

EEF2K (HGNC Symbol)

Synonyms

eEF-2K

Description

eukaryotic elongation factor-2 kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]

Chromosome

16 (Chromosome progress)

Cytoband

p12.2

Chromosome location (bp)

22217603 - 22298554

Ensembl

ENSG00000103319 (version 73.37)

Entrez gene

29904

UniProt

O00418 (UniProt - Evidence at protein level)

neXtProt

NX_O00418

Antibodypedia

EEF2K antibodies
 

PROTEIN VIEW

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EEF2K-001
 
EEF2K-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EEF2K-001 ENSP00000263026
ENST00000263026
O00418
Show all »
Show » Show » 725 82.1 No 0
EEF2K-002 ENSP00000456243
ENST00000568269
H3BRH4
Show all »
Show » 412 46.7 No 0