DNAJA3

GENE INFORMATION

? »

Gene name

DNAJA3 (HGNC Symbol)

Synonyms

hTid-1, TID1

Description

DnaJ (Hsp40) homolog, subfamily A, member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

4475806 - 4506776

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103423 (version 75.37)

Entrez gene

9093

UniProt

Q96EY1 (UniProt - Evidence at protein level)

neXtProt

NX_Q96EY1

Antibodypedia

DNAJA3 antibodies
 

PROTEIN VIEW

? »
 
 
 
DNAJA3-001
 
DNAJA3-002
 
DNAJA3-003
 
DNAJA3-006
 
DNAJA3-007
 
DNAJA3-009
 
DNAJA3-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNAJA3-001 ENSP00000262375
ENST00000262375
Q96EY1
Show all »
Show » Show » 480 52.5 No 0
DNAJA3-002 ENSP00000347445
ENST00000355296
Q96EY1
Show all »
Show » Show » 453 49.6 No 0
DNAJA3-003 ENSP00000459098
ENST00000576911
I3L1T9
Show all »
Show » 98 10.4 No 0
DNAJA3-006 ENSP00000458868
ENST00000575106
I3L1I6
Show all »
Show » 122 13.1 No 0
DNAJA3-007 ENSP00000460358
ENST00000570857
I3L3D3
Show all »
Show » 77 8 No 0
DNAJA3-009 ENSP00000459088
ENST00000574895
I3L1T6
Show all »
Show » Show » 185 20.4 No 0
DNAJA3-201 ENSP00000393970
ENST00000431375
E7ES32
Show all »
Show » Show » 300 33.1 No 0