CTSH

GENE INFORMATION

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Gene name

CTSH (HGNC Symbol)

Synonyms

ACC-4, ACC-5, CPSB

Description

cathepsin H (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq, Mar 2010]

Chromosome

15 (Chromosome progress)

Cytoband

q25.1

Chromosome location (bp)

79213400 - 79241916

Ensembl

ENSG00000103811 (version 73.37)

Entrez gene

1512

UniProt

P09668 (UniProt - Evidence at protein level)

neXtProt

NX_P09668

Antibodypedia

CTSH antibodies
 

PROTEIN VIEW

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CTSH-001
 
CTSH-002
 
CTSH-003
 
CTSH-007
 
CTSH-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CTSH-001 ENSP00000220166
ENST00000220166
P09668
Show all »
Show » Show » 335 37.4 Yes 0
CTSH-002 ENSP00000432935
ENST00000525807
E9PN60
Show all »
Show » 118 12.6 Yes 0
CTSH-003 ENSP00000431879
ENST00000533777
Show » 62 6.8 Yes 0
CTSH-007 ENSP00000435329
ENST00000528741
E9PKT6
Show all »
Show » 134 14.7 No 0
CTSH-008 ENSP00000432893
ENST00000529861
E9PN84
Show all »
Show » 41 4.3 Yes 0