CD276

GENE INFORMATION

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Gene name

CD276 (HGNC Symbol)

Synonyms

B7-H3, B7H3, B7RP-2

Description

CD276 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

15 (Chromosome progress)

Cytoband

q24.1

Chromosome location (bp)

73976307 - 74006859

Ensembl

ENSG00000103855 (version 73.37)

Entrez gene

80381

UniProt

Q5ZPR3 (UniProt - Evidence at protein level)

neXtProt

NX_Q5ZPR3

Antibodypedia

CD276 antibodies
 

PROTEIN VIEW

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CD276-001
 
CD276-002
 
CD276-003
 
CD276-006
 
CD276-007
 
CD276-008
 
CD276-012
 
CD276-014
 
CD276-015
 
CD276-016
 
CD276-017
 
CD276-018
 
CD276-019
 
CD276-020
 
CD276-021
 
CD276-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD276-001 ENSP00000454940
ENST00000564751
Q5ZPR3
Show all »
Show » Show » 316 33.8 Yes 1
CD276-002 ENSP00000320084
ENST00000318443
Q5ZPR3
Show all »
Show » Show » 534 57.2 Yes 1
CD276-003 ENSP00000452736
ENST00000561213
Q5ZPR3
Show all »
Show » Show » 533 57.2 Yes 1
CD276-006 ENSP00000453330
ENST00000560928
H0YLT3
Show all »
38 4 Yes 0
CD276-007 ENSP00000441087
ENST00000537340
Q5ZPR3
Show all »
Show » Show » 388 41.8 No 1
CD276-008 ENSP00000453842
ENST00000559073
Show » Show » 170 18.2 No 1
CD276-012 ENSP00000453014
ENST00000561176
Show » Show » 199 21.3 No 1
CD276-014 ENSP00000453907
ENST00000558689
H0YN85
Show all »
Show » Show » 136 14.5 Yes 0
CD276-015 ENSP00000452669
ENST00000561260
H0YK59
Show all »
Show » Show » 165 17.6 Yes 0
CD276-016 ENSP00000453336
ENST00000560995
H0YLT8
Show all »
Show » Show » 133 14.2 Yes 0
CD276-017 ENSP00000452905
ENST00000561416
H0YKQ9
Show all »
Show » Show » 51 5.2 Yes 0
CD276-018 ENSP00000455366
ENST00000567189
H0YLT8
Show all »
Show » Show » 133 14.2 Yes 0
CD276-019 ENSP00000456657
ENST00000567582
H0YLT3
Show all »
38 4 Yes 0
CD276-020 ENSP00000454258
ENST00000563584
H3BM68
Show all »
Show » Show » 146 15.7 No 1
CD276-021 ENSP00000452649
ENST00000560786
H0YK40
Show all »
Show » Show » 156 16.7 Yes 0
CD276-201 ENSP00000320058
ENST00000318424
Q5ZPR3
Show all »
Show » Show » 316 33.8 Yes 1