RIPK2

GENE INFORMATION

? »

Gene name

RIPK2 (HGNC Symbol)

Synonyms

CARD3, CARDIAK, RICK, RIP2

Description

receptor-interacting serine-threonine kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]

Chromosome

8 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

90769975 - 90803291

Ensembl

ENSG00000104312 (version 73.37)

Entrez gene

8767

UniProt

O43353 (UniProt - Evidence at protein level)

neXtProt

NX_O43353

Antibodypedia

RIPK2 antibodies
 

PROTEIN VIEW

? »
 
 
 
RIPK2-001
 
RIPK2-002
 
RIPK2-003
 
RIPK2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RIPK2-001 ENSP00000220751
ENST00000220751
O43353
Show all »
Show » Show » 540 61.2 No 0
RIPK2-002 ENSP00000429271
ENST00000522965
E7ERW9
Show all »
Show » 68 7.6 No 0
RIPK2-003 ENSP00000427736
ENST00000517696
E5RGK6
Show all »
Show » 70 7.8 No 0
RIPK2-201 ENSP00000441623
ENST00000540020
O43353
Show all »
Show » Show » 403 45.6 No 0