STK3

GENE INFORMATION

? »

Gene name

STK3 (HGNC Symbol)

Synonyms

KRS1, MST2

Description

serine/threonine kinase 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Chromosome

8 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

99413631 - 99955055

Ensembl

ENSG00000104375 (version 73.37)

Entrez gene

6788

UniProt

Q13188 (UniProt - Evidence at protein level)

neXtProt

NX_Q13188

Antibodypedia

STK3 antibodies
 

PROTEIN VIEW

? »
 
 
 
STK3-001
 
STK3-002
 
STK3-004
 
STK3-005
 
STK3-006
 
STK3-016
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STK3-001 ENSP00000390500
ENST00000419617
Q13188
Show all »
Show » Show » 491 56.3 No 0
STK3-002 ENSP00000429744
ENST00000523601
B3KYA7
Show all »
Show » Show » 519 59.5 No 0
STK3-004 ENSP00000428167
ENST00000424861
Q8NBU1
Show all »
Show » Show » 168 18.9 No 0
STK3-005 ENSP00000428014
ENST00000518165
E5RFQ9
Show all »
Show » 229 26.1 No 0
STK3-006 ENSP00000429369
ENST00000521649
E5RIM6
Show all »
Show » 82 9.2 No 0
STK3-016 ENSP00000428295
ENST00000519420
1 0.1 No 0